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Xiǎo Huí Xiāng 小茴香

Pharmaceutical name Foeniculi Fructus Foeniculum vulgare Fennel fruit
Category Warm Interior, Expel Cold
Key Properties Harmonizes the Middle
Warms the Lower Burner
Treats bulging disorders
Properties Acrid
Warm
Tropism LV, KD, SP, ST
Actions & Indications 1) Disperses Cold, Warms Liver & Kidneys, and Stops Pain
(Cold Shan (bulging) disorder)
2) Regulates the Qi and Harmonizes the Stomach
Dosages 3-9g
Contraindications (TCM) CI: Blazing Fire with Yin Def; caution during pregnancy
Contraindications (Western)
Chemical Composition Essential oil 3-6% (trans-anethole, limonene, fenchone, estragole, ɣ-terpinene, α-pinene, mycene, β-pinene, camphor, camphene, methoxyphenyl acetone, sabinene, α-phellandrene, p-cymene, cineole, 4-terpineol, transfenchol acetate, anethole, anisaldenyde), petroselinic acid
Pharmacological Effects • Gastrointestinal: various effects on gastrointestinal system; stimulates smooth muscle to increase peristalsis; also exerts inhibitory effect on secretion of gastric acid
• Effect on the liver: one study found that continuous administration of essential oil of Xiao Hui Xiang for 10 days increases weight of liver; has been proposed that the herb may promote regeneration of liver cells
Herb-Drug Interactions • Ciprofloxacin: absorption and disposition of ciprofloxacin in rats may be affected when given concurrently with Xiao Hui Xiang; in one study, rats were divided into two groups with one receiving ciprofloxacin only and the other receiving both ciprofloxacin and Xiao Hui Xiang; blood and urine samples were collected after 6 and 24 hours and analyzed by HPLC; compared with control group, study found that there was a decrease of maximum plasma concentration by 83%, of area under the curve by 48%, and of urinary recovery by 43% in treatment group; furthermore, apparent volume of distribution and terminal half-life were both increased; mechanism of herb-drug interaction attributed to high content of metal cations present in the herb; researchers concluded that if the two agents are to be used concurrently, an adequate dosing interval is required to ensure efficacy of ciprofloxacin
Classical Formula(s)

Nuan Gan Jian (Warm the Liver Decoction) 暖肝煎



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This information is a reference tool for Chinese herbal studies. It is not intended to replace professional medical advice. Please consult a primary health professional if you require health advisory.