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Bǔ Gǔ Zhī 補骨脂

Pharmaceutical name Psoraleae Fructus Psoralea fruit "tonify bone fat"
Category Tonify Yang
Key Properties Warmly tonifies KD and SP, Stabilizes the essence, Secures the urine, Aids KD in grasping Qi
Properties Acrid
Bitter
Very warm
Tropism KD, SP
Actions & Indications 1) Tonifies the KD and fortifies the yang
2) Tonifies and warms the SP yang and Stops diarrhea
3) Topically as a tincture for vitiligo
Dosages 4.5-9g
Contraindications (TCM) Yin Deficiency with heat signs, constipation, nocturnal emissions, hematuria, cystitis or urinary tract infection, red eyes, bitter taste in mouth with a dry tongue
Caution during pregnancy
Contraindications (Western)
Chemical Composition Psoralen, isopsoralen, coryfolin, corylifolinin, psoralidin, isopsoralidin, corylidin, 8-methoxyporalen, isobavahin, bavachinin, bavachalcone, bavachromenn, bavachromanol, corylin, neobavaisofavane, corylinal, bakuchiol, psoraldehyde, isoneobavachalion, dihydrofuranochalcone bakuchalcone, chalcone bavachromanol, neobavachalcone, limonene, terpineol, stigmasterol, trilaurin, daidzin, coumstrol, angelicin
Pharmacological Effects • Cardiovascular: administration dilates coronary artery and increases blood perfusion to cardiac muscle in mice
• Respiratory: in a laboratory study, preparation found to have marked antiasthmatic properties compared to a placebo
• Antibiotic: inhibitory effect against S. aureus, Staphylococcus albus, and others
• Immunostimulant: administration associated with increase in white blood cell counts in rats
• Effects on smooth muscle: according to animal studies, extract stimulated smooth muscle of intestines, but relaxed smooth muscle of uterus
• Antineoplastic: preliminary studies demonstrated that psoralen at 250 µg/ml inhibits DNA synthesis of cancer cells in patients with sarcoma
Herb-Drug Interactions
Classical Formula(s)

Qi Bao Mei Ran Dan (Seven treasure special pill for beautiful whiskers) 七寶美髯丸

Si Shen Wan (Four-Miracle Pill) 四神丸



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This information is a reference tool for Chinese herbal studies. It is not intended to replace professional medical advice. Please consult a primary health professional if you require health advisory.