Single Herb Glossary
Dì Yú 地榆
| Pharmaceutical name | Sanguisorbae Radix sanguisorba, burnet-bloodwort root |
| Category | Stop Bleeding |
| Key Properties | cools heat in the blood, stops bleeding, resolves toxicity, restrains and inhibits |
| Properties | Bitter Sour Slightly Cold |
| Tropism | LV, LI, ST |
| Actions & Indications | 1) Cool Blood & Stop Bleeding (lower jiao dysfunction, hemorrhaging, uterine bleeding) 2) Clears heat and generates flesh (topically for sores/ulcers/burns) |
| Dosages | 9-15g |
| Contraindications (TCM) | Caution in those with cold from deficiency or blood stasis; bleeding from deficiency, cold or blood stasis |
| Contraindications (Western) | |
| Chemical Composition | Ziyuglycoside I, ziyuglycoside II, sanguisorbin, sanguisorbigenin tannins |
| Pharmacological Effects | • Hemostatic: oral administration of unprocessed Di Yu powder and charred Di Yu powder to mice, at 5 g/kg, reduced bleeding time by 31.9% and 45.5% respectively; oral administration of unprocessed Di Yu powder and charred Di Yu powder to rabbits, at 2 g/kg, reduced bleeding time by 25% in both groups • Effect on relief of burns: topical application of powder in dogs and rabbits with second and third degree burns showed marked effectiveness in reducing swelling and inflammation by decreasing vascular permeability; it lowered risk of infection, shortened recovery time, and minimized risk of shock • Antibiotic: water extract exhibits inhibitory influence on Salmonella typhi, Diplococcus meningitidis, β-hemolytic streptococcus, S. aureus, and Diplococcus pneumoniae; alcohol extract exerts inhibitory effect on E. coli and Bacillus subtilis • Antiemetic: decoction at 3 g/kg given orally twice daily for 2 days, effective in controlling vomiting in pigeons induced by digitalis tincture, but ineffective for vomiting in dogs induced by apomorphine; antiemetic effect similar to 0.25 mg/kg of intramuscular injection of chlorpromazine • Anti-inflammatory: water and alcohol extracts have demonstrated marked anti-inflammatory effects |
| Herb-Drug Interactions | • Ciprofloxacin: has been suggested that absorption and disposition of ciprofloxacin may be affected when given concurrently with herb; to avoid drug-herb interaction and interference with bioavailability of ciprofloxacin, adequate time should be allowed between intake of drug and herb to ensure efficacy of ciprofloxacin if the two agents were to be used concurrently |
| Classical Formula(s) |
This information is a reference tool for Chinese herbal studies. It is not intended to replace professional medical advice. Please consult a primary health professional if you require health advisory.