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Dì Gǔ Pí 地骨皮

Pharmaceutical name Lycii Cortex Barbary wolfberry root bark “earth bone bark”
Category Clear Heat from Deficiency
Key Properties Eliminates heat from both excess & deficiency in the blood
Cools the Lungs
Properties Sweet
Bland
Cold
Tropism LU, LV, KD
Actions & Indications 1) Cools Blood & Reduces Steaming (steaming bone with sweating)
2) Clears & drains LU heat: cough, wheezing
3) External Wash for Genital Itching combined with other herbs (KD Fire: toothache)
Dosages 6-15g
50g+ - vertigo, palpitations, nausea/vomiting, premature contractions
Contraindications (TCM) Exterior Wind-Cold or Wind-Heat
Caution in patients who have true Cold but false Heat
SP and ST Deficiency with loose stool

No toxic side-effects if within normal dosage
Contraindications (Western)
Chemical Composition Betaine, lyciumins A, B; kukoamine A, lyciumamide, cinnamic acid
Pharmacological Effects • Antibiotic: inhibits activity of typhoid, paratyphoid and shigella
• Antihypertensive: intravenous injection of preparation in anesthetized dogs, cats and rats lowered blood pressure by 53%, 67%, and 27%, respectively; alcohol extracts and kukoamine A also have antihypertensive effects; lyciumins A and B are angiotensin converting enzyme (ACE) inhibitors, and have marked effects to lower blood pressure
• Antipyretic: both oral and intravenous administrations of water and alcohol extracts have marked effectiveness in reducing body temperature in rabbits
• Antidiabetic: oral ingestion of decoction at 8 g/kg lowered blood glucose in healthy rabbits by 14% for up to 7 or 8 hours
Herb-Drug Interactions
Classical Formula(s)

Qin Jiao Bie Jia San (Large gentian and Soft-Shelled Turtle Shell Powder) 秦艽鱉甲散

Qing Gu San (Cool the Bones Powder) 清骨散

Xie Bai San (Drain the White Powder) 瀉白散 (泻白散)



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This information is a reference tool for Chinese herbal studies. It is not intended to replace professional medical advice. Please consult a primary health professional if you require health advisory.